Series Vol. 6 , 03 August 2023
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With the development of food processing, public concern was aroused by safety issues regarding the application of artificial additives. Ultra-ultra-processed food is made through a process by adding additives such as antioxidants, preservatives, and coloring agents to modify the properties of the food product and cater to customer demands. This essay focuses on food chemistry to research how additives present in ultra-processed food affect health. Moreover, common food additives used in food processing and their potential threats will be discussed. The fact is that many cases have proved that sodium benzoate, vitamin C, vitamin E, Yellow No.5, and Yellow No.6 do have an impact on human health. Other types of additives such as those present in nature do not have a significant relationship with cancer molarity and health problems. There need further studies on the relationship between synthesized additives and carcinogenicity. The purpose of studying chemical additives is to understand the chemical properties behind food additives will inform people of the actual harmful ingredients in ultra-processed food and avoid large dose intake.
food chemistry, processed food, food additives
1. International Food Information Council, “FOOD SAFETY: consumer trends, habits, attitudes,” (2019).
2. World Health Organization, “Food additives,” (2018).
3. Monteiro, C., Cannon, G., Moubarac, J., Levy, R., Louzada, M., & Jaime, P., “The UN Decade of Nutrition, the NOVA food classification and the trouble with ultra-processing,” Public Health Nutrition, 21(1), 5-17 (2018).
4. Marc J. Gunter, Fernanda Rauber, Renata B. Levy, Inge Huybrechts, Nathalie Kliemann, Christopher Millett, Eszter P. Vamos., “Ultra-processed food consumption, cancer risk, and cancer mortality: a large-scale prospective analysis within the UK Biobank,” eClinicalMedicine, 56: 101840 (2023).
5. Cancer.Net. “Food and Cancer Risk,” American Society of Clinical Oncology, (2019).
6. Kebede M, Admassu S., “Application of antioxidants in food processing industry: Options to improve the extraction yields and market value of natural products,” Adv Food Technol Nutr Sci Open J., 5(2): 38-49 (2019)
7. Parohan, M., Anjom-Shoae, J., Nasiri, M., et al. “Dietary total antioxidant capacity and mortality from all causes, cardiovascular disease and cancer: a systematic review and dose–response meta-analysis of prospective cohort studies,” Eur J Nutr 58, 2175–2189 (2019).
8. Young IS, Woodside JV., “Antioxidants in health and disease,” Journal of Clinical Pathology, 54: 176-186 (2001).
9. Morelli, M. B., Gambardella, J., Castellanos, V., Trimarco, V., & Santulli, G. Vitamin C and Cardiovascular Disease: An Update. Antioxidants (Basel, Switzerland), 9(12), 1227 (2020).
10. Ritu Gupta, Dr. Rakesh Kumar Yadav, “Impact Of Chemical Food Preservatives On Human Health,” PalArch’s Journal of Archaeology of Egypt / Egyptology, 18(15), 811 – 818 (2021).
11. World Health Organization & International Programme on Chemical Safety, “Benzoic acid and sodium benzoate,” World Health Organization, (2000).
12. Subhashish Dey, Bommu Hema Nagababu, “Applications of food color and bio-preservatives in the food and its effect on the human health,” Food Chemistry Advances, Volume 1, 100019, ISSN 2772-753X (2022).
13. Shahmohammadi M, Javadi M, Nassiri-Asl M. “An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products,” Biotech Health Sci, 3(3):e35084 (2016).
14. Julie N. Barrows, Ph.D., Arthur L. Lipman, Ph.D., and Catherine J. Bailey, M.Ed. Series Editor: Sebastian Cianci, Food and Drug Administration, “Color Additives History” (2017).
15. Lobo, V., Patil, A., Phatak, A., & Chandra, N., “Free radicals, antioxidants, and functional foods: Impact on human health,” Pharmacognosy reviews, 4(8), 118–126 (2010).
16. Gaber El-Saber Batiha, Diaa E. Hussein, Abdelazeem M. Algammal, Toyosi T. George, Philippe Jeandet, Ali Esmail Al-Snafi, Achyut Tiwari, Jorge Pamplona Pagnossa, Clara Mariana Lima, Nanasaheb D. Thorat, Muhammad Zahoor, Mohamed El-Esawi, Abhijit Dey, Saad Alghamdi, Helal F. Hetta, Natália Cruz-Martins, “Application of natural antimicrobials in food preservation: Recent views,” Food Control, Volume 126, 108066, ISSN 0956-7135 (2021).
17. Eberechukwu S, Amadikwa A, Okechukwu M. “Effect of oral intake of sodium benzoate on some hematological parameters of Wistar albino rats,” Sci Res Essays. 2(1): 6-9 (2017).
18. Cortés‐Jofré M, Rueda JR, Asenjo‐Lobos C, Madrid E, Bonfill Cosp X. Drugs for preventing lung cancer in healthy people. “Cochrane Database of Systematic Reviews 2020,” Issue 3. Art. No.: CD002141, (2020).
19. Véronique Bouvard, Dana Loomis, Kathryn Z Guyton, Yann Grosse, Fatiha El Ghissassi, Lamia Benbrahim-Tallaa, Neela Guha, Heidi Mattock, Kurt Straif. “Carcinogenicity of consumption of red and processed meat,” Volum 16, Issue 16, P1599-1600 (2015).
20. Claire McCarthy, M., “Common food additives and chemicals harmful to children,” Harvard Health Publishing, (2021).
21. Harrington, R., “Does Artificial Food Coloring Contribute to ADHD in Children?,” (2015).
22. Kannarek, R. B., “Artificial food dyes and attention deficit hyperactivity disorder,” Nutrition Reviews, 385-391 (2011).
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.