Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences

Theoretical and Natural Science

Vol. 24, 20 December 2023

Open Access | Article

Industrial pollutions on the health effects of infants, children, and adolescents: A systematic review

Zeqiang Wang * 1
1 Shanghai Starriver Bilingual School

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 24, 65-70
Published 20 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Zeqiang Wang. Industrial pollutions on the health effects of infants, children, and adolescents: A systematic review. TNS (2023) Vol. 24: 65-70. DOI: 10.54254/2753-8818/24/20231101.


Industrial pollution is considered especially harmful to juveniles’ health. This paper analyzes the effect of common pollutants, including particulate matter, nitrogen oxides, persistent organic pollutants, and heavy metals, on three different types of diseases. It can be concluded that particulate matter, nitrogen oxide, and POPs are significantly associated with neurodevelopmental deficiencies in infants. Endocrine-disrupting effects and neuroinflammation are considered the leading causes, but the specific mechanisms remain questioned. Pollutants from heavy industries have a higher potential to cause children’s respiratory diseases, and residency within 4 km of the industry is especially hazardous. Biomarkers VEGF and urinary 8-OHdG reflect a high glutathione-related oxidative burden for exposure to toxic metals attached to particulate matter. Deregulation in metabolism and DNA oxidative damage is shown to be responsible for increasing cancer risk, but the triggering pathway is unclear. The tendency to develop diseases in both genders is heterozygous, and a larger dataset is required to draw a conclusion.


industrial pollution, PM2.5, POPs, children, health


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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
ISBN (Print)
ISBN (Online)
Published Date
20 December 2023
Theoretical and Natural Science
ISSN (Print)
ISSN (Online)
20 December 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated