Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 27, 20 December 2023


Open Access | Article

The application of gene editing in treating cancer

Yu xuan Yang * 1
1 ShangHai DTD Academy

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 27, 76-80
Published 20 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Yu xuan Yang. The application of gene editing in treating cancer. TNS (2023) Vol. 27: 76-80. DOI: 10.54254/2753-8818/27/20240677.

Abstract

Current gene editing technology mainly involves inserting, replacing or deleting DNA sequences to change the genetic material of an organism, and its most common aspects are using this technology to mass-produce some drugs, such as insulin, or using gene editing to change some nutrients in plants to help others. This article use a literature review and, expects to give an extensive outline of the utilizations of quality altering in medication, with a specific spotlight on its utilization in cancer disease treatment. The paper finds that gene editing technology has emerged as a powerful tool in the field of medicine, revolutionizing the treatment of diseases, including cancer and some systemic diseases. There are many different diseases in the world that currently have no cure, because medicine needs to go through many stages before it can be brought to market and given to people, but through gene editing technology can greatly help alleviate or even reverse these diseases. Other than that, this research deepens our understanding of biology, thereby contributing to the future connection between biotechnology development and medicine, and helping more patients with difficult and complex diseases.

Keywords

Ene editing, medicine, cancer, DNA sequence, CRISPR

References

1. Zang Qijie Research on the Ethical Risks and Countermeasures of Gene Editing Technology [D]. Nanjing Forestry University, 2023. DOI: 10.27242/d.cnki. gnjlu.2022.000115

2. Zhang Qiang, Gu Mingliang. Gene editing technology and its clinical application [J]. Chemistry of Life, 2022, 42 (01): 41-55. DOI: 10.13488/j.smhx.20210674

3. Dai X, Blancafort P, Wang P, Sgro A, Thompson EW, Ostrikov KK. Innovative Precision Gene-Editing Tools in Personalized Cancer Medicine. Adv Sci (Weinh). 2020 Apr 23;7(12):1902552. doi: 10.1002/advs.201902552. PMID: 32596104; PMCID: PMC7312441.

4. NCI. “How CRISPR Is Changing Cancer Research and Treatment - National Cancer Institute.” Www.cancer.gov, National Cancer Institute, 27 July 2020, www.cancer.gov/news-events/cancer-currents-blog/2020/crispr-cancer-research-treatment.

5. Zhang H, Qin C, An C, Zheng X, Wen S, Chen W, Liu X, Lv Z, Yang P, Xu W, Gao W, Wu Y. Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer. Mol Cancer. 2021 Oct 1;20(1):126. doi: 10.1186/s12943-021-01431-6. PMID: 34598686; PMCID: PMC8484294.

6. Wu Jiadong, Xiao Rui. The off target effect of CRISPR/Cas9 system and its application in non coding RNA editing mediated by it in human cancer [J]. Chongqing Medical Journal, 2018,47 (18): 2480-2483+2486

7. Tufail, Muhammad. “Genome Editing: An Essential Technology for Cancer Treatment.” Medicine in Omics, vol. 4, June 2022, p. 100015, https://doi.org/10.1016/j.meomic.2022. 100015. Accessed 30 June 2022.

8. Maity S, Mukherjee R, Banerjee S. Recent Advances and Therapeutic Strategies Using CRISPR Genome Editing Technique for the Treatment of Cancer. Mol Biotechnol. 2023 Feb;65(2):206-226.doi: 10.1007/s12033-022-00550-9. Epub 2022 Aug 23. PMID: 35999480.

9. Wang Dayong, Ma Ning, Hui Yang et al. Application of CRISPR/Cas9 genome editing technology in cancer research [J]. Genetics, 2016,38 (01): 1-8. DOI: 10.16288/j.yczz.15-252

10. Ella S. Atsavapranee; Margaret M. Billingsley; Michael J. Mitchell; (2021). Delivery technologies for T cell gene editing: Applications in cancer immunotherapy. EBioMedicine.

Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Authors who publish this series agree to the following terms:

1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this series.

2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this series.

3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See Open Access Instruction).

Volume Title
Proceedings of the 2nd International Conference on Modern Medicine and Global Health
ISBN (Print)
978-1-83558-237-4
ISBN (Online)
978-1-83558-238-1
Published Date
20 December 2023
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/27/20240677
Copyright
20 December 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated