Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences

Theoretical and Natural Science

Vol. 24, 20 December 2023

Open Access | Article

Research on the application of microRNA in hepatocellular carcinoma

Jinrong Geng * 1
1 Shenyang Pharmaceutical University

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 24, 40-44
Published 20 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Jinrong Geng. Research on the application of microRNA in hepatocellular carcinoma. TNS (2023) Vol. 24: 40-44. DOI: 10.54254/2753-8818/24/20231092.


The digestive tract frequently develops the malignant tumor known as hepatocellular carcinoma (HCC). A variety of liver diseases can develop into HCC and therefore a therapeutic approach is required. Extracellular vesicles known as exosomes are released by a number of cells and contain a wide range of active substances, including lipids, proteins, RNA, and DNA. microRNA is a type of RNA that accelerates apoptosis by participating in the regulation of downstream gene translation. Studies have shown that exosomal micrornas regulate HCC. Exosomal microRNAs have been proven in studies which regulate HCC. Exosomal micrornas may therefore be particular biomarkers for HCC metastases and early diagnosis as well as possible therapeutic targets. The utilization of exosomal micrornas in HCC is employed as biomarkers for early diagnosis and may trigger cancer cell apoptosis through the PI3K-AKT channel or MAPKs/ERK channel to produce therapeutic effects. Exosomal micrornas are briefly detailed in this paper.


microRNAs, HCC, exosomes, application


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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
ISBN (Print)
ISBN (Online)
Published Date
20 December 2023
Theoretical and Natural Science
ISSN (Print)
ISSN (Online)
20 December 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated