Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 27, 20 December 2023
Open
Access | Article
Progress in the application of gene editing technology in cancer treatments—taking CRISPR as an example
* Author to whom correspondence should be addressed.
Abstract
The background of CRISPR’s development lies in the long-standing need for precise gene editing tools, which culminated in the revolutionary CRISPR-Cas9 system in 2012. This technology has had profound impacts on biology, medicine, and biotechnology, offering versatile applications in gene therapy, agriculture, and research across eukaryotes, prokaryotes, and archaea. In the context of cancer research, CRISPR has shown promise in understanding cancer biology, identifying therapeutic targets, enhancing immunotherapy, and potentially enabling early cancer diagnosis and personalized treatment. However, challenges remain, including the need to enhance precision, address ethical concerns, and conduct rigorous clinical trials. This article examines CRISPR’s advancements in cancer treatment and concludes that, when compared to other gene editing methods, it offers benefits like robust targeting, easy operation, and efficient editing. Based on these benefits, the application prospect of CRISPR in enhancing personalized medicine, drug development, and cancer treatment is also discussed in this article. This article highlights the need for addressing precision and safety issues and the importance of interdisciplinary collaboration and stringent regulation in realizing the full potential of CRISPR in cancer treatment. In conclusion, CRISPR offers promising avenues for improving cancer treatment by enabling precise gene editing and personalized therapies. Despite the challenges, continuous advancements in technology and research, along with stricter regulation, will ensure the safe and effective use of CRISPR in cancer, providing hope for cancer patients and shaping the future of oncology research.
Keywords
CRIPR-Cas9, cancer treatments, research progress.
References
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3. Herrera-C E et al 2020 CRISPR therapy towards an HIV cure Briefings in Functional Genomics 193 201-208
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5. Volke D C et al P I 2023 Emergent CRISPR–Cas-based technologies for engineering non-model bacteria Curr Opin Microbiol 75 102353
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Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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- Volume Title
- Proceedings of the 2nd International Conference on Modern Medicine and Global Health
- ISBN (Print)
- 978-1-83558-237-4
- ISBN (Online)
- 978-1-83558-238-1
- Published Date
- 20 December 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/27/20240708
- Copyright
- 20 December 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited