Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 20, 20 December 2023
Open
Access | Article
CRISPR/Cas base-editing systems and their potential applications and prospects
* Author to whom correspondence should be addressed.
Abstract
CRISPR-Cas9 and its derivatives such as cytosine base editor, adenine base editor and prime editing are an important topic of research today. In recent years, with continuous development and updates by researchers, editing systems have been able to achieve various modifications of target genes. For example, base substitution, insertion and deletion of short fragment genes, etc. have wide applications in plants and animals, etc. However, these editing systems derived from the CRISPR/Cas9 system still face challenges in terms of editing efficiency and accuracy. This review describes the current status of research using editing systems in plant breeding, gene disease treatment, and knockdown of specific genes by establishing animal models, analyzes the advantages and disadvantages of editing technologies, and looks forward to their development.
Keywords
CRISPR/Cas system, DNA base editing, gene editing
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Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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- Volume Title
- Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
- ISBN (Print)
- 978-1-83558-213-8
- ISBN (Online)
- 978-1-83558-214-5
- Published Date
- 20 December 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/20/20230739
- Copyright
- 20 December 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited