Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 3, 28 April 2023
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Research Progress in Pathogenesis and Treatment of the Anterior Cruciate Ligament Injury
* Author to whom correspondence should be addressed.
Abstract
With the continuous development of the sports in China, sports trauma is also on the rise year by year, of which the former cruciate ligament injury is quite common. Anterior cruciate ligament (ACL), one of the two main types of intraarticular fibrous ligament, it can provide the rotational and translational stability for the knee. When it injurys, patients' exercise ability and life well-being will decline, and even lead to a series of complications, especially in women. The risk of the ACL injury in the women is almost 3.5 times that in men. There are many factors leading to ACL injury. Studies have shown that after anterior cruciate ligament injury, most patients choose surgical treatment. With the development of the Arthroscopic technique, most of the patients would be likely to choose the surgical treatment, especially the people that are young and active. The surgical treatment have several advantages, like the post-operative recovery is fast, less traumatic, fewer complications. At present, the surgical treatment is mainly reconstruction under arthroscopy. The reconstruction materials include autografts, allografts, artificial ligaments and so on. It is necessary to understand the difference of biochemical and biological characteristics of different grafts in the process of ligament healing. For some elderly patients or patients with other special needs, non-surgical treatment can also be selected. This article reviews the pathogenic factors, surgical methods, grafts, and other aspects for clinical reference.
Keywords
Anterior cruciate ligament injury, pathogenesis, treatment
References
1. E. C. Rodríguez-Merchán. Anterior Cruciate Ligament Reconstruction: Is Biological Augmentation Beneficial? Int J Mol Sci. 2021 Nov 22;22(22):12566. [2] A.M.Montalvo, D. K. Schneider, L. Yut, K. E. Webster, B. Beynnon, M. S 2021 Nov22;22(22): 12566.
2. A.M.Montalvo, D. K. Schneider, L. Yut, K. E. Webster, B. Beynnon, M. S. Kocher, G. D. Myer "What's my risk of sustaining an ACL injury while playing sports?" A systematic review with meta-analysis. Br J Sports Med. 2019 Aug;53(16):1003-1012.
3. 2018 International Olympic Committee consensus statement on prevention, diagnosis and management of paediatric anterior cruciate ligament (ACL) injuries. Knee Surg Sports Traumatol Arthrosc.2018 Apr;26(4):989-1010.
4. A. V. Stone, S. Marx, C. W. Conley. Management of Partial Tears of the Anterior Cruciate Ligament: A Review of the Anatomy, Diagnosis, and Treatment. J Am Acad Orthop Surg. 2021 Jan 15;29(2):60-70.
5. A. A. Amis,G. P. Dawkins. Functional anatomy of the anterior cruciate ligament. Fibre bundle actions related to ligament replacements and injuries. J Bone Joint Surg Br. 1991 Mar;73(2):260-7.
6. J. Evans, J. L. Nielson. Anterior Cruciate Ligament Knee Injuries. 2022 May 5. In: StatPearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2022 Jan–. PMID: 29763023.
7. L. Herrington, C. Nester. Q-angle undervalued? The relationship between Q-angle and mediolateral position of the patella. Clin Biomech 2004; 19 (10): 1070-7.
8. A. Akhavi Milani, Motallebzadeh Khanamiri M, Mahmoudpour M. The geometric features of tibiofemoral joint associated with anterior cruciate ligament injury: Reliability of measurements on conventional MRI. Eur J Radiol Open. 2022 Apr 5;9:100420.
9. E. Hohmann, K. Tetsworth, V. Glatt ,M. Ngcelwane, N. Keough. Medial and Lateral Posterior Tibial Slope Are Independent Risk Factors for Noncontact ACL Injury in Both Men and Women. Orthop J Sports Med. 2021 Aug 12;9(8):23259671211015940.
10. Z. Liu, J. Jiang, Q. Yi, Y. Teng, X. Liu, J. He, K. Zhang, L. Wang, F. Teng, B. Geng, Y. Xia, M. Wu. An increased posterior tibial slope is associated with a higher risk of graft failure following ACL reconstruction: a systematic review. Knee Surg Sports Traumatol Arthrosc. 2022 Feb 6.
11. T. M. Ellison, I. Flagstaff, A. E. Johnson. Sexual Dimorphisms in Anterior Cruciate Ligament Injury: A Current Concepts Review. Orthop J Sports Med. 2021 Dec 17;9(12):23259671211025304.
12. C. E. Pfeifer, P. F. Beattie, R. S. Sacko, A. Hand. RISK FACTORS ASSOCIATED WITH NON-CONTACT ANTERIOR CRUCIATE LIGAMENT INJURY: A SYSTEMATIC REVIEW. Int J Sports Phys Ther. 2018 Aug;13(4):575-587.
13. A. Sandon, W. Krutsch, V. Alt, M. Forssblad. Increased occurrence of ACL injuries for football players in teams changing coach and for players going to a higher division. Knee Surg Sports Traumatol Arthrosc. 2022 Apr;30(4):1380-1387.
14. M. C. Hong, Research advances in anterior cruciate ligament injury, Chinese Manipulation and Rehabilitation Medicine,2021,Vol.12 No.4.
15. R. G. Marx, K. Yin, C. C. Kaeding AAOS Appropriate Use Criteria: Treatment of Anterior Cruciate Ligament Injuries. J Am Acad Orthop Surg. 2016 Aug;24(8):e84-6.
16. A. Maestro, I. Herruzo, D. Varillas-Delgado, C. Martín-Saborido. Subjective assessment reported by patients shows differences between single-bundle and double-bundle anterior cruciate ligament reconstruction, systematic review and meta-analysis. Sci Rep. 2021 Jul 28;11(1):15385.
17. H. Chen, B. Chen, K. Tie, Z. Fu, L. Chen. Single-bundle versus double-bundle autologous anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials at 5-year minimum follow-up. J Orthop Surg Res. 2018 Mar 10;13(1):50.
18. K. M. Lin, C. Boyle, N. Marom, R. G. Marx. Graft Selection in Anterior Cruciate Ligament Reconstruction. Sports Med Arthrosc Rev. 2020 Jun;28(2):41-48.
19. T. A. Burkhart, T. Hoshino, L. M. Batty, A. Blokker, P. P. Roessler, R. Sidhu, M. Drangova, D. W. Holdsworth, I. Petrov, R. Degen, A. M. Getgood. No Difference in Ligamentous Strain or Knee Kinematics Between Rectangular or Cylindrical Femoral Tunnels During Anatomic ACL Reconstruction With a Bone-Patellar Tendon-Bone Graft. Orthop J Sports Med. 2021 Jun 10;9(6):23259671211009523.
20. T. Sun, H. Zhang. Biomechanical Comparison of a Novel Tibial Fixation Technique Versus Interference Screw Fixation for ACL Reconstruction Using Soft Tissue Grafts. Orthop J Sports Med. 2021 Aug 25;9(8):23259671211028559.
21. B. A. Zhao, Y. Y. Yao, Q. X. Ji, Z. Y. Li, B. Cheng, J. F. Pan. No difference in postoperative efficacy and safety between autograft and allograft in anterior cruciate ligament reconstruction: a retrospective cohort study in 112 patients. Ann Transl Med. 2022 Mar;10(6):359.
22. L. Guo, L. Yang, X. J. Duan, R. He, G. X. Chen, F. Y. Wang, Y. Zhang. Anterior cruciate ligament reconstruction with bone-patellar tendon-bone graft: comparison of autograft, fresh-frozen allograft, and g-irradiated allograft. Arthroscopy 2012 Feb;28(2):211.
23. D. Fan, J. Ma, L. Zhang. Patellar tendon versus artificial grafts in anterior cruciate ligament reconstruction: a systematic review and meta-analysis. J Orthop Surg Res. 2021 Aug 4;16(1):478.
24. H. Q. Qing, Q. Shuang, Research advances in rehabilitation for anterior cruciate ligament injuries, Chin J Sports Med, Sep. 2017 ,Vol.36, No.9
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- Volume Title
- Proceedings of the 2nd International Conference on Biological Engineering and Medical Science (ICBioMed 2022), Part I
- ISBN (Print)
- 978-1-915371-25-6
- ISBN (Online)
- 978-1-915371-26-3
- Published Date
- 28 April 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/3/20220195
- Copyright
- 28 April 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited