Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 4, 28 April 2023
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Human Senescence: Fundamental Causes, Telomere Shortening and Consequences
* Author to whom correspondence should be addressed.
Abstract
Senescence, also known as biological aging, is the gradual deterioration of functional characteristics in living organisms. Human civilization has spent tremendous efforts dealing with senescences in the past centuries. In the process of senescence, cellular and genetic-based materials face several variations, and they can be varied beneficially by preventing cancer cell development, such as tumor cells. However, it surely will result in several problems due to cellular senescence. Moreover, factors contributing to human senescence will be elaborated in the following review paper. Telomere will be one factor that plays an essential role in growing old. Due to its unique characteristic of shortening, the ability to repair after the replication will be heavily reduced. Thus, this review intended to illustrate the overall process of human senescence, which involves fundamental causes of senescence, telomere shortening, and its consequences.
Keywords
Reactive oxygen species, Senescence, Telomere, Type-2 diabetes
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Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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- Volume Title
- Proceedings of the 2nd International Conference on Biological Engineering and Medical Science (ICBioMed 2022), Part II
- ISBN (Print)
- 978-1-915371-27-0
- ISBN (Online)
- 978-1-915371-28-7
- Published Date
- 28 April 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/4/20220527
- Copyright
- 28 April 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited