Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 8, 13 November 2023
Open
Access | Article
Comprehensive research progress in stem cell therapy
* Author to whom correspondence should be addressed.
Abstract
Stem cell therapy is increasingly recognized as an innovative and transformative approach in the field of medicine, with the potential to address tissue damage and manage intricate medical conditions. The utilization of induced pluripotent stem cells (iPSCs) presents a potential avenue for cardiac regeneration in the context of cardiovascular ailments, such as myocardial infarctions. Liver regeneration techniques utilizing mesenchymal stem cells (MSCs) are being offered as potential solutions for end-stage liver failure. Furthermore, stem cell therapy is regarded as a promising intervention for neurodegenerative disorders and ocular conditions, with disease-specific induced pluripotent stem cells (iPSCs) emerging as a frontrunner in prospective therapeutic approaches. The objective of this study is to investigate the advancements made in stem cell therapy research for the diseases mentioned above. It will involve a comprehensive analysis of the mechanisms and principles underlying stem cell treatment in these areas, as well as an examination of the factors that impede the progress of stem cell therapy. Additionally, this paper will offer insights into potential future directions for development in this field.
Keywords
Stem Cell Therapy, Mesenchymal Stem Cells, Pluripotent Stem Cells
References
1. Bartunek, J., Behfar, A., Dolatabadi, D., Vanderheyden, M., Ostojic, M., Dens, J., El Nakadi, B., Banovic, M., Beleslin, B., Vrolix, M., Legrand, V., Vrints, C., Vanoverschelde, JL., Crespo-Diaz, R., Homsy, C., Tendera, M., Waldman, S., Wijns, W., Terzic, A. (2014). Cardiopoietic Stem Cell Therapy in Heart Failure: The C-CURE (Cardiopoietic stem Cell therapy in heart failURE) Multicenter Randomized Trial With Lineage-Specified Biologics. Journal of the american college of cardiology, 62(25), 2457-2458. https://doi.org/10.1016/j.jacc.2013.02.071
2. Miotti, G., Parodi, PC., Zeppieri, M. (2021). Stem cell therapy in ocular pathologies in the past 20 years. World Journal of Stem Cells, 13(5), 1-24. https://doi.org/10.4252/wjsc.v13.i5.366
3. Fang, J., J. Li, J., Zhong, XT., Zhou Y., J. Lee, R., Cheng, K., Li, S. (2022). Engineering stem cell therapeutics for cardiac repair. Journal of Molecular and Cellular Cardiology, 171, 56-68. https://doi.org/10.1016/j.yjmcc.2022.06.013
4. Wang, J., Sun, MY., Liu, W., Li, Y., Li, M. (2019). Stem Cell-Based Therapies for Liver Diseases: An Overview and Update. Tissue Engineering and Regenerative Medicine, 16, 107–118. https://doi.org/10.1007/s13770-019-00178-y
5. Yuan, MQ., Hu, X., Yao, LC., Jiang, YA., Li, LJ. (2022). Mesenchymal stem cell homing to improve therapeutic efficacy in liver disease. Stem Cell Research & Therapy, 13(1), 1-17. https://doi.org/10.1186/s13287-022-02858-4
6. Ahani-Nahayati, M., Shariati, A., Mahmoodi, M., Zekiy, AO., Javidi, K.,Shamlou, S., Mousakhani, A., Zamani, M., Hassanzadeh, A. (2021). Stem cell in neurodegenerative disorders; an emerging strategy. International Journal of Developmental Neuroscience, 81(4), 291-311. https://doi.org/10.1002/jdn.10101
7. Wang, MY., Yang, XM., Zhang, P., Cai, L., Yang, XB., Chen, YW., Jing, YY., Kong, JL., Yang, XW., Sun, FL. (2016). Sustained Delivery Growth Factors with Polyethyleneimine-Modified Nanoparticles Promote Embryonic Stem Cells Differentiation and Liver Regeneration. Adv Sci, 3(8), 1-13. https://doi.org/10.1002/advs.201500393
Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Authors who publish this series agree to the following terms:
1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this series.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this series.
3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See Open Access Instruction).
- Volume Title
- Proceedings of the 2nd International Conference on Modern Medicine and Global Health
- ISBN (Print)
- 978-1-83558-111-7
- ISBN (Online)
- 978-1-83558-112-4
- Published Date
- 13 November 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/8/20240363
- Copyright
- 13 November 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited