Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 22, 20 December 2023


Open Access | Article

Research progress and preventive strategy of HPV and cervical cancer and other related cancers

Ziyanran Wang * 1
1 Xiehe Bilingual Experimental School

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 22, 53-59
Published 20 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Ziyanran Wang. Research progress and preventive strategy of HPV and cervical cancer and other related cancers. TNS (2023) Vol. 22: 53-59. DOI: 10.54254/2753-8818/22/20230935.

Abstract

This paper comprehensively reviews the research on the relationship between HPV and cervical cancer and other cancers and expounds the pathogenesis of cancer caused by HPV and its negative impact on the body. The screening methods and their effectiveness are reviewed, and the relevant research and latest developments of vaccines are summarized. First, the basic knowledge about HPV (including the structure and typing of the virus and the mechanism of infection of the virus) is introduced, and the screening method and its effectiveness are explored. Furthermore, the relationship between cervical cancer and HPV infection (including the mechanism of occurrence, the type of virus that causes cervical cancer, and the characteristics after infection) is discussed emphatically. Subsequently, the relationship between HPV infection and other cancers (including the mechanism of infection, classification and post-infection characteristics) was further explored, such as oral cancer, anal cancer, and reproductive organ cancer (except cervical cancer that has been introduced above). In the end, the current research results on HPV prevention and the challenges to be met from the current point of view are summarized, and the outlook and some suggestions for the research direction of future vaccines are made.

Keywords

HPV, vaccines, cancer

References

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3. Ntuli, L., Mtshali, A., Mzobe, G., Liebenberg, L. J., & Ngcapu, S. (2022). Role of Immunity and Vaginal Microbiome in Clearance and Persistence of Human Papillomavirus Infection. Frontiers in cellular and infection microbiology, 12, 927131.

4. Gutiérrez-Hoya, A., & Soto-Cruz, I. (2020). Role of the JAK/STAT Pathway in Cervical Cancer: Its Relationship with HPV E6/E7 Oncoproteins. Cells, 9(10), 2297.

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8. National Cancer Institute. “HPV and Cancer.” National Cancer Institute, Cancer.gov, 31 Jan. 2023, www.cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-and-can-cer. Accessed 9 June 2023.

9. Omland, S. H., Ahlström, M. G., Gerstoft, J., Pedersen, G., Mohey, R., Pedersen, C., Kronborg, G., Larsen, C. S., Kvinesdal, B., Gniadecki, R., Obel, N., & Omland, L. H. (2018). Risk of skin cancer in patients with HIV: A Danish nationwide cohort study. Journal of the American Academy of Dermatology, 79(4), 689–695.

10. Szymonowicz, K. A., & Chen, J. (2020). Biological and clinical aspects of HPV-related cancers. Cancer biology & medicine, 17(4), 864–878.

11. Kamolratanakul, S., & Pitisuttithum, P. (2021). Human Papillomavirus Vaccine Efficacy and Effectiveness against Cancer. Vaccines, 9(12), 1413.

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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
ISBN (Print)
978-1-83558-217-6
ISBN (Online)
978-1-83558-218-3
Published Date
20 December 2023
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/22/20230935
Copyright
20 December 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated