Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 23, 20 December 2023
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Exploring the utilization of polylactic acid-based materials in medicine: Contemporary innovations and trends
* Author to whom correspondence should be addressed.
Abstract
A biocompatible, non-toxic substance is polylactic acid (PLA), which is also biodegradable. This material has been studied for decades and has been commercially used in some fields. The potential of defined PLA for different medical applications, including drug delivery systems, wound healing, bone implants, and vascular grafts, was described in this paper. Various methods of characterization and modification of PLA have been investigated to optimize its properties for specific applications. Typically, additional polymers are introduced into PLA to enhance its functional properties. The key feature of PLA is its capacity for degradation in the human body without introducing harmful byproducts. Adjustments to PLA composition can control degradation rates, influencing drug delivery or the persistence of implants. By applying a cold plasma treatment in order to alter the PLA-based polymer's surface, the capacity of the material to transport drugs may be changed. The change of parameters in coaxial electrospinning can produce different PLA-based products for different use. However, certain challenges remain, such as improving the adhesion of PLA and production of low-price PLA.
Keywords
polylactic acid, drug delivery, wound healing, implant, vascular graft
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Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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- Volume Title
- Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
- ISBN (Print)
- 978-1-83558-219-0
- ISBN (Online)
- 978-1-83558-220-6
- Published Date
- 20 December 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/23/20231021
- Copyright
- 20 December 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited