Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences

Theoretical and Natural Science

Vol. 6, 03 August 2023

Open Access | Article

Analysis on the effect of genes on amyotrophic lateral sclerosis

Jiayi Zang * 1
1 Shenzhen MSU-BIT University

* Author to whom correspondence should be addressed.

Advances in Humanities Research, Vol. 6, 229-233
Published 03 August 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Jiayi Zang. Analysis on the effect of genes on amyotrophic lateral sclerosis. TNS (2023) Vol. 6: 229-233. DOI: 10.54254/2753-8818/6/20230230.


Amyotrophic Lateral Sclerosis (ALS) is a progressive weakness and atrophy of the muscles including the bulb (the part of the muscles innervated by the medulla oblongata), limbs, trunk, chest, and abdomen following injury to upper and lower motor neurons. However, the reasons for developing ALS are still not very clear. Both genetic defects and environmental factors may damage motor neurons. At present, ALS is a difficult disease to cure. For environmental factors, people can change their lifestyles to reduce or avoid the effects of the environment. However, inherited genetic defects are hard to avoid. Therefore, in this paper, the author explores the treatment of ALS by analyzing and summarizing a large number of papers and experimental studies learning the relationship between genes and ALS. In conclusion, the gene TARDBP and the gene C9ORF72 were found in a large number of disease-causing genes. Mutations in these genes can lead to changes in the encoded proteins that cause the development of ALS disease.




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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the International Conference on Modern Medicine and Global Health (ICMMGH 2023)
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ISBN (Online)
Published Date
03 August 2023
Theoretical and Natural Science
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© 2023 The Author(s)
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

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