Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 27, 20 December 2023
Open
Access | Article
The study on the relationship between dementia and air pollution
* Author to whom correspondence should be addressed.
Abstract
Dementia is a multifaceted neurological condition distinguished by a reduction in cognitive abilities, impairment of memory function, and worsening in overall functional capacity. In recent times, there has been an increasing level of apprehension regarding the potential consequences of environmental elements, specifically air pollution, on the advancement and manifestation of dementia. The primary objective of this research article is to investigate the correlation between dementia and air pollution by a comprehensive analysis of epidemiological data. Additionally, this study will delve into probable processes that may underlie this association and then analyze the ramifications for public health. The results indicate that the presence of air pollution could potentially be a contributing factor to an elevated susceptibility to dementia and a deterioration in cognitive function among those afflicted. Gaining a comprehensive understanding of this correlation is of utmost importance in order to formulate efficacious preventive measures and policies aimed at mitigating the adverse effects of air pollution on dementia.
Keywords
dementia, air pollution, neurodegenerative disorder, cognitive decline, epidemiology, public health
References
1. Chen H, Kwong JC, Copes R, et al. Living near major roads and the incidence of dementia, Parkinson’s disease, and multiple sclerosis: a population-based cohort study. Lancet. 2017;389(10070):718-726.
2. Oudin A, Forsberg B, Adolfsson AN, et al. Traffic-related air pollution and dementia incidence in Northern Sweden: a longitudinal study. Environ Health Perspect. 2016;124(3):306-312.
3. Chang KH, Chang MY, Muo CH, Wu TN, Hwang BF, Chen CY. Increased risk of dementia in patients exposed to nitrogen dioxide and carbon monoxide: a population-based retrospective cohort study. PLoS One. 2017;12(6):e0177860.
4. Wu YC, Lin YC, Yu HL, Chen JH, Chen TF, Sun Y, et al. Association between air pollutants and dementia risk in the elderly. Alzheimers Dement. 2015;11(7):P415.
5. Peters R, Ee N, Peters J, Booth A, Mudway I, Anstey KJ. Air pollution and dementia: a systematic review. J Alzheimers Dis. 2019;70(s1):S145-S163.
6. Calderón-Garcidueñas L, Franco-Lira M, Henríquez-Roldán C, et al. Urban air pollution: influences on olfactory function and pathology in exposed children and young adults. Exp Toxicol Pathol. 2010;62(2):91-102.
7. Block ML, Elder A, Auten RL, et al. The outdoor air pollution and brain health workshop. Neurotoxicology. 2012;33(5):972-984.
8. Calderón-Garcidueñas L, D’Angiulli A, Kulesza RJ, et al. Air pollution and children: neural and tight junction antibodies and combustion metals, the role of barrier breakdown and brain immunity in neurodegeneration. J Alzheimers Dis. 2015;43(3):1039-1058.
9. Calderón-Garcidueñas L, Reed W, Maronpot RR, et al. Brain inflammation and Alzheimer’s-like pathology in individuals exposed to severe air pollution. Toxicol Pathol. 2004;32(6):650-658.
10. Fonken LK, Xu X, Weil ZM, Chen G, Sun Q, Rajagopalan S, et al. Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology. Mol Psychiatry. 2011;16(10):987-995.
Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Authors who publish this series agree to the following terms:
1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this series.
2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this series.
3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See Open Access Instruction).
- Volume Title
- Proceedings of the 2nd International Conference on Modern Medicine and Global Health
- ISBN (Print)
- 978-1-83558-237-4
- ISBN (Online)
- 978-1-83558-238-1
- Published Date
- 20 December 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/27/20240594
- Copyright
- 20 December 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited