Theoretical and Natural Science
- The Open Access Proceedings Series for Conferences
Theoretical and Natural Science
Vol. 16, 04 December 2023
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Predictive value of Caprini score, D-dimer, and PLT for venous thromboembolism in high-altitude
* Author to whom correspondence should be addressed.
Abstract
Objective: This study aimed to identify early warning indicators for predicting venous thromboembolism (VTE) in Tibetan patients with respiratory system diseases at the Respiratory Intensive Care Unit of People’s Hospital in Lhasa City by analyzing relevant clinical data. Methods: From September 2021 to August 2023, Tibetan patients with respiratory system diseases treated in the hospital’s Respiratory and Critical Care Medicine Department were categorized into non-VTE and VTE groups based on VTE occurrence. We compared baseline and admission 24-hour examination data between the groups and performed logistic regression analysis to identify VTE-associated indicators. These relevant indicators underwent COX regression analysis and inter-indicator correlation analysis. Results: The study included 717 Tibetan patients with respiratory system diseases, with 582 in the non-VTE group and 135 in the VTE group. Significant differences were observed between the two groups in age, pulse, respiration, white blood cell count, hematocrit, platelet count, prothrombin time, D-dimer, total bilirubin, blood urea nitrogen, uric acid, Caprini score, and D-dimer-to-platelet ratio (D-DI/PLT) (p < 0.05). Logistic regression analysis identified white blood cell count, hematocrit, prothrombin time, Caprini score, and D-DI/PLT as significantly associated with VTE occurrence. COX curve analysis indicated that Caprini score and D-DI/PLT could predict VTE without correlation between them. Conclusion: Caprini score and D-DI/PLT can serve as predictors of VTE in Tibetan patients with respiratory system diseases. Particularly, D-DI/PLT, easily obtainable, can guide clinical stratified treatment in these patients.
Keywords
Venous Thromboembolism, Caprini Score, D-dimer, Platelets, Highland, Tibetan
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Data Availability
The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.
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- Volume Title
- Proceedings of the 2nd International Conference on Modern Medicine and Global Health
- ISBN (Print)
- 978-1-83558-195-7
- ISBN (Online)
- 978-1-83558-196-4
- Published Date
- 04 December 2023
- Series
- Theoretical and Natural Science
- ISSN (Print)
- 2753-8818
- ISSN (Online)
- 2753-8826
- DOI
- 10.54254/2753-8818/16/20240537
- Copyright
- 04 December 2023
- Open Access
- This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited