Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 23, 20 December 2023


Open Access | Article

Research on the gene therapy and prevention of lung cancer

Handa Liu * 1
1 Tianjin Medical University

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 23, 103-107
Published 20 December 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Handa Liu. Research on the gene therapy and prevention of lung cancer. TNS (2023) Vol. 23: 103-107. DOI: 10.54254/2753-8818/23/20231032.

Abstract

In recent years, there have been significant advancements in molecular biology, gene therapy technology, and high-tech testing techniques. As our understanding of the pathogenesis of lung cancer continues to deepen, it has become evident that gene therapy plays a crucial role in its treatment. This article provides an overview of tumor cell development, various gene therapy techniques including suicide gene therapy, silent gene therapy, cancer suppressor genetic therapy, and antibody genetic therapy. Additionally, it analyzes the application value, treatment technology, and safety concerns associated with gene therapy. The discussion also covers the safety issues and current application status of viral and nonviral vectors in gene therapy, comparing the advantages and disadvantages of different vector types. Furthermore, the article summarizes the future directions for designing and improving gene delivery vectors, along with their clinical application prospects. Ultimately, this article offers insights into the significance and treatment approaches for early prevention of lung cancer.

Keywords

gene therapy, delivery vectors, tumor therapy, P53 gene, lung cancer prevention

References

1. Yang Jiao & Sun Fu. (2018). Research progress of nucleic acid delivery vectors for gene therapy. Journal of Shanxi Medical University (03), 310-315. doi:10.13753/j.issn. 1007-6611.2018.03.022.

2. Huimin Xu, Jianqiao Chang, Yunchao Li, Xiaohong Li, Wenjing Xie, Yang Zhang & Luzhen Fan. (2022). Advances in nanomaterials in gene therapy: from tumor therapy to new coronavirus vaccines. Journal of Beijing Normal University (Natural Science Edition) (04),535-546.

3. Zhou Caicun & Corn Bo. (2006). Advances in the mechanism of apoptosis and repair in lung cancer. International Respiratory Journal (02),122-124+133.

4. Wu, J. & Bai, P.. (2006).Progress in the study of the relationship between p53 and human lung cancer. International Respiratory Journal(02),99-102.

5. Yang, Liu, Huang, C. & Wang, M.X.. (2020). Advances in gene therapy research for cancer. Medical Information (03), 1-5.

6. Kim, Yuanwu & Wang, Zhehai. (2006). Current status of gene therapy for lung cancer. Medical Review(02),75-77.

7. Ji-Wen Zhang, Gui-Lian Yang & Chun-Feng Wang. (2010). Current status and prospects of retroviral vectors. Biotechnology(04),89-92.

8. Zhao Junli&Xia Haibin (2010). Labeling Methods for Adenoviruses. Chemistry of Life (04), 640-643 Doi: 10.13488/j.smhx.2010.04.025

9. Zhang, Yang. (2014). Research progress of lentiviral vectors. Journal of Fujian Medical University(06),407-410.

10. Zhang Yansong, Chen Lijiao, Zhang Ting, Ma Yue & Li Shangang. 2011 A new species of the genus Pseudomonas (Hymenoptera, Braconidae) from China. (2020). Research progress in gene therapy. Chinese Journal of Cell Biology (10), 1858-1869.

11. Gao Yang,Li Weimin. (2005). Research progress in lung cancer prevention. Western medicine(03),252-253.

Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the 3rd International Conference on Biological Engineering and Medical Science
ISBN (Print)
978-1-83558-219-0
ISBN (Online)
978-1-83558-220-6
Published Date
20 December 2023
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/23/20231032
Copyright
20 December 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated