Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 29, 16 January 2024


Open Access | Article

Vagus nerve stimulation on epilepsy and depression

Yuxiao Lin * 1
1 New York Institute of Technology

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 29, 131-135
Published 16 January 2024. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Yuxiao Lin. Vagus nerve stimulation on epilepsy and depression. TNS (2024) Vol. 29: 131-135. DOI: 10.54254/2753-8818/29/20240760.

Abstract

This review presents an overview of vagus nerve stimulation (VNS) utilization. The vagus nerve (VN) is among the most versatile and important nerves, with the capability to regulate a few bodily functions, and has been playing a vital role as part of therapies for a range of health concerns. VNS is an effective therapeutic method, which has gotten the approval of the Food and Drug Administration (FDA) of the United States. It is a type of neurostimulation method that plays a crucial part in drug-resistant depression and refractory epilepsy. It provides a surgical option for patients suffering from the conditions mentioned above, and is rather effective compared with other surgical approaches, thus improving patients’ life quality. Despite side effects, it is considered a decent therapeutic method and is currently used widely clinically. Furthermore, the mechanisms of VNS have not been completely understood. Therefore, further research is necessary, to discover the potential of VNS as an additional therapy for various other medical conditions.

Keywords

Vagus nerve stimulation, vagus nerve, epilepsy, depression

References

1. Howland RH 2014 Curr Behav Neurosci Rep 1(2) 64

2. Krahl SE 2012 Surg Neurol Int 3(1) 47

3. Prescott SL, Liberles SD 2022 Neuron 110(4) 579

4. Johnson RL, Wilson CG 2018 J Inflamm Res 11 203

5. Eibhlin Goggins, Shuhei Mitani, Shinji Tanaka 2022 Clin Sci (Lond) 136 (9) 695

6. Mark S. George, Harold A. Sackeim, A.John Rush, Lauren B. Marangell, Ziad Nahas, Mustafa M. Husain, Sarah Lisanby, Tal Burt, Juliet Goldman, et al. 2000 Biological Psychiatry 47 287

7. Möbius H, Welkoborsky HJ 2022 Laryngorhinootologie 101(S 01) S114

8. Boluk C, Ozkara C, Isler C, Uzan M 2022 Turk Neurosurg 32(1) 97

9. Winter Y, Sandner K, Glaser M, Ciolac D, Sauer V, Ziebart A, Karakoyun A, Chiosa V, Saryyeva A, Krauss J, Ringel F, et al. 2023 J Neurol. 270(10) 4978

10. Fan JJ, Shan W, Wu JP, Wang Q. 2019 CNS Neurosci Ther. 25(11) 1222

11. Elger G., Hoppe C., Falkai P., Rush A.J. and Elger C.E 2000 Epilep. Res. 42 203

12. Liu CH, Yang MH, Zhang GZ, Wang XX, Li B, Li M, Woelfer M, Walter M, Wang L. 2020 J Neuroinflammation. 17(1) 54

13. Bajbouj M., Merkl A., Schlaepfer T.E., Frick C., Zobel A., Maier W. et al. 2010 J. Clin. Psychopharmacol. 30 273

14. Eibhlin Goggins, Shuhei Mitani, Shinji Tanaka. 2022 Clin Sci (Lond) 136 (9) 695

15. Capilupi MJ, Kerath SM, Becker LB. 2020 Cold Spring Harb Perspect Med. 10(2) a034173

16. Khodaparast, N., Hays, S.A., Sloan, A.M., Fayyaz, T., Hulsey, D.R., Rennaker, R.L. et al. 2014 Neurorehabil. Neural Rep. 28 698

17. Liu YL, Wang SR, Ma JX, Yu LH, Jia GW. 2023 Neural Regen Res. 18(4) 825.

18. Dawson J, Liu CY, Francisco GE, Cramer SC, Wolf SL, Dixit A, Alexander J, Ali R, Brown BL, Feng W, et al.2021 Lancet. 397(10284) 1545

Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. Authors who publish this series agree to the following terms:

1. Authors retain copyright and grant the series right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this series.

2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the series's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this series.

3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See Open Access Instruction).

Volume Title
Proceedings of the 2nd International Conference on Modern Medicine and Global Health
ISBN (Print)
978-1-83558-279-4
ISBN (Online)
978-1-83558-280-0
Published Date
16 January 2024
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/29/20240760
Copyright
16 January 2024
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated