Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 6, 03 August 2023


Open Access | Article

CRISPR-Cas9 as a tool for treating cystic fibrosis through gene editing

Jiabao Xu * 1
1 Chongqing Depu Foreign Language School

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 6, 191-197
Published 03 August 2023. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Jiabao Xu. CRISPR-Cas9 as a tool for treating cystic fibrosis through gene editing. TNS (2023) Vol. 6: 191-197. DOI: 10.54254/2753-8818/6/20230222.

Abstract

The most common cause of mortality is Cystic Fibrosis, a fatal genetic disease. However, in recent years, there have been a growing number of papers concentrating on CRISPR-Cas9, a gene-editing tool that is being used to permanently cure this genetic disease, named by a biopharmaceutical company EditasMedicine, invested in by Bill Gates. However, before the breadth of search and study of this technology continuously expands, challenges and remaining issues should be addressed. This paper reviews the mechanisms of cystic fibrosis and discusses its technical challenges, such as efficiency, safety and delivery of gene editing, potential side effects, and ethical issues, this paper also talks about the future applications of CRISPR-Cas9 in other diseases, so as to provide an alternative treatment method for the diseases with gene editing better results can be obtained.

Keywords

cystic fibrosis, CRISPR-Cas9, gene edit, CFTR

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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the International Conference on Modern Medicine and Global Health (ICMMGH 2023)
ISBN (Print)
978-1-915371-65-2
ISBN (Online)
978-1-915371-66-9
Published Date
03 August 2023
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/6/20230222
Copyright
03 August 2023
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated