Theoretical and Natural Science

- The Open Access Proceedings Series for Conferences


Theoretical and Natural Science

Vol. 39, 21 June 2024


Open Access | Article

Design and simulation of a bioimpedance detection analog front-end targeting medical applications

Xiaorui Mo 1 , Jiayu Zhu 2 , Hanxiao Lu 3 , Xu Liu * 4
1 Beijing University of Technology
2 Beijing University of Technology
3 Beijing University of Technology
4 Beijing University of Technology

* Author to whom correspondence should be addressed.

Theoretical and Natural Science, Vol. 39, 112-120
Published 21 June 2024. © 2023 The Author(s). Published by EWA Publishing
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citation Xiaorui Mo, Jiayu Zhu, Hanxiao Lu, Xu Liu. Design and simulation of a bioimpedance detection analog front-end targeting medical applications. TNS (2024) Vol. 39: 112-120. DOI: 10.54254/2753-8818/39/20240615.

Abstract

This paper presents the design of a bio-impedance detection analog front-end system, which is critical for continuous monitoring of physiological signals in the prevention and treatment of diseases such as coronary heart disease in the context of an aging population. The analog front-end system employs a capacitive-coupled chopper instrumentation amplifier with a fully differentially folded cascode operational amplifier as the core amplifier, and a common-mode feedback loop is introduced to improve the common-mode rejection ratio due to the high requirement for noise suppression. The power supply voltage of the design is 3.3V, achieving a total current consumption of 45uA and a total power consumption of 0.15mW. The core operational amplifier provides a maximum open-loop gain of 58 dB and a -3dB bandwidth of 8.2KHz. The power supply rejection ratio for the positive supply and ground achieved values of 102dB and 108dB, respectively. The common-mode rejection ratio of the chopper instrumentation amplifier can reach 109 dB, which is critical for suppressing common-mode noise.

Keywords

bio-signal acquisition, analog-front-end (AFE), instrumentation amplifier (IA), common-mode rejection ratio (CMRR), chopper modulation

References

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Data Availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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Volume Title
Proceedings of the 2nd International Conference on Mathematical Physics and Computational Simulation
ISBN (Print)
978-1-83558-463-7
ISBN (Online)
978-1-83558-464-4
Published Date
21 June 2024
Series
Theoretical and Natural Science
ISSN (Print)
2753-8818
ISSN (Online)
2753-8826
DOI
10.54254/2753-8818/39/20240615
Copyright
21 June 2024
Open Access
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Copyright © 2023 EWA Publishing. Unless Otherwise Stated